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Purinethol uses: Used to treat leukemia. Also is used to treat many types of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, acute idiopathic polyneuritis, acute idiopathic nephrotic syndrome, psoriatic arthritis, erythroid aplasia, or myelofibrosis; idiopathic hemolytic anemia; macroglobulinemia; idiopathic thrombocytopenia purpura; idiopathic pulmonary hemosiderosis; multiple sclerosis; myasthenia gravis; uveitis; and ulcerative colitis

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